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CR: COVID-19 --Political Talk


Mrs Whiggins

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Relevant. 
 

Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection

https://www.nejm.org/doi/full/10.1056/NEJMc2202092?

The median time from the initial positive PCR assay to culture conversion was 4 days (interquartile range, 3 to 5) in the delta group and 5 days (interquartile range, 3 to 9) in the omicron group; the median time from symptom onset or the initial positive PCR assay, whichever was earlier, to culture conversion was 6 days (interquartile range, 4 to 7) and 8 days (interquartile range, 5 to 10), respectively. There were no appreciable between-group differences in the time to PCR conversion or culture conversion according to vaccination status, although the sample size was quite small, which led to imprecision in the estimates (Figure 1D and 1E).

 

E7-C90-B5-C-9056-4-C4-C-802-D-6581234238

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6 minutes ago, NameAlreadyInUse said:

Maybe it's been a long week, or maybe I'm just dumb.  Can you translate that to layman's terms, @Anastasis?

Some small sample size evidence that describes the time from initial symptom onset/positivity to when the individual is no longer shedding culturable virus.  Median time to conversion (no longer shedding) was 8 days for omicron, with a substantial portion shedding up to and beyond 10 days. CDC guidance for strict isolation period was reduced from 10 to 5 days. These data suggest 5 days is probably too short a time frame for a general recommendation.

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I need to read it, but if you have the answer -- were the participants in the study regularly PCR tested prior to infection/symptom or was this all anecdotal patient info?

I would think PCR might tend to register positive prior to symptom onset.

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41 minutes ago, jimmyjazz said:

I need to read it, but if you have the answer -- were the participants in the study regularly PCR tested prior to infection/symptom or was this all anecdotal patient info?

I would think PCR might tend to register positive prior to symptom onset.

From the appendix with more details on the methods...

 

30 Methods

31 Study Participants

32 Non-hospitalized individuals with positive SARS-CoV-2 PCR tests in the Mass General Brigham
33 medical system were recruited (Supplementary Figure S4). Adults over 18 years of age with a
34 positive test within the previous four days in the medical health record were recruited,
35 irrespective of indication for testing (i.e. for symptomatic disease, contact tracing, or work or pre
36 operative screening). The study team extracted an automated list of positive COVID-19 tests
37 from the electronic medical record. The list was restricted to individuals residing in the study
38 catchment area- a 40-mile radius around the hospital established by the need to conduct home
39 based specimen collection. At the start of each week, patients with positive results were
40 stratified by vaccination status and ranked by recency of positive result with the goal of
41 recruiting 2-3 new participants per week, which was the maximum capacity of the team to
42 conduct ambulatory specimen collection. For those who consented to participation, we
43 conducted home visits three times weekly for two weeks or until negative PCR testing

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On 7/6/2022 at 10:21 PM, Bama Chick said:


The lingering symptoms you are describing are textbook Long COVID. If the doc is downplaying those, look for a second opinion from a specialist.

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Add depression.  My friend from ATL whose been battling this tells me the depression is so hard to break through.  It's so tiring to just get up.  

But on a better note, she is better.  She regained 25% of her lung capacity but she is still on disability but they are letting her drive Uber for a little side income without threatening the disability.  It's not much, but she is still fighting.  She's spent 30% of her days either in a hospital or some sort or convalescent center since she caught it back in Sept of 20.     

I hope she's past the worst of it.  Seems to be, but still so far to go.   

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(yesterday) Day 20:  I woke-up and was feeling a little better with a bit more energy.  I was able to stand longer without getting dizzy.   I was in a little disbelief when I tested Negative 3x with BinaxNOW(2) and FlowFlex (1) test kits.   I packed up, cleaned up, and went home.  The clean-up process which would have normally taken about an hour took about 2.5 hours.   I surprised my kids and my eldest was in tears.  It was like those military homecoming videos.   

Issues:    Night sweats, malaise.  Stamina and mental fatigue is still an issue.

Improvements:   I am a little more mentally alert. I have a little more stamina than I had only a few days ago.  A little more head congestion/allergy symptoms today which is most likely related to my environment change. 

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13 minutes ago, SaucyJack said:

Where in the Philippines are your kids going to school?

Just read the introduction, and the kid basically fucking off while his mom does his work seems to indicate some other issues are at hand. 

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10 minutes ago, DDD Dad said:

I got mine on Sunday. It kicked my ass for 36 hours. 

I had the fourth a couple of months ago.  I have had reactions to all of the shots, I think #4 may have been the mildest, although my injection arum hurt like a mofo.  

Thankfully, and bizarrely, the bilateral shoulder pain that cropped up has resolved.

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Day 32 (after testing positive) and 13 days after negative Antigen testing (3x):

At home with the family and I am capable of participating nearly full time.  I started reading (not kids books) and I am capable of doing so in short durations (20 minutes).

Improvements:  Night sweats ended.  Stamina is improving and I am able to stand for longer periods of time without getting light headed.  I can cook without taking a break and stopped burning things.   Concentration really improved this week. 

Lingering Issues:  I still get a little lightheaded from time to time and but it is usually after some exertion on my part, for example I cut down a wild tree that was growing in my backyard and I had enough energy to take off the tops, but not enough to remove the root structure.   I ended up fatigued and a little lightheaded after that.   Overall I am returning more to normal but am just a weakened version.  

I called my allergist and they informed me that I could visit 2 weeks after my negative test, per their policy.   There is so much variability in how the medical community handles this.   Recall my primary suggested it would be fine to visit even while being positive after a number of days.

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56 minutes ago, Nivek said:

I called my allergist and they informed me that I could visit 2 weeks after my negative test, per their policy.   There is so much variability in how the medical community handles this.   Recall my primary suggested it would be fine to visit even while being positive after a number of days.

I'd imagine it's all different levels of risk acceptance. A PCP is likely going to be facing a higher baseline risk of COVID exposure than the allergist by the nature of their practice - the allergist likely has fewer people coming to them specifically when they're feeling sick

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3 hours ago, TwiceHorn said:

I had the fourth a couple of months ago.  I have had reactions to all of the shots, I think #4 may have been the mildest, although my injection arum hurt like a mofo.  

Thankfully, and bizarrely, the bilateral shoulder pain that cropped up has resolved.

 

2 hours ago, jimmyjazz said:

Luckily, I've had exactly zero side effects from any of the 4 shots.

This one was by far the worst reaction.  Chills and basically feeling shitty starting about 8 hours after the injection that lasted over 24 hours, plus some mild soreness near the injection site and in that armpit for a couple of days (stopped aching sometime late yesterday).

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I honestly don't know why I don't get reactions.  Science doesn't seem to indicate there is much of a correlation between immune health and reaction, and I haven't caught covid (to my knowledge). 

I had many of the symptoms in Feb 2020, but they started just a few hours after my (late season) flu vaccine, so I thought that WAS a vaccine reaction.  Then again, I did have a dry cough for a couple of weeks, so maybe.

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1 hour ago, Captainant said:

I'd imagine it's all different levels of risk acceptance. A PCP is likely going to be facing a higher baseline risk of COVID exposure than the allergist by the nature of their practice - the allergist likely has fewer people coming to them specifically when they're feeling sick

Sorry for wording that poorly.  The Primary suggested it should be OK for me to visit the Allergist with a positive antigen testing and to be around my family with little kids but not to see my dentist.   The Allergist response is basically, your Primary is wrong about us.  

 

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1 minute ago, justhookit said:

Jesus fuck why include his vaccination status in the headline. I mean we know but there are150 million idiots out there that will say see, vaccinations don’t work.

For people of average intelligence or higher, they will understand that being fully vaccinated greatly improves Biden's chance of getting through COVID quickly and yes, surviving it. 

My opening disclaimer eliminates a fair amount of the GOP.

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1 hour ago, 4th&Five said:

 

 

9 minutes ago, HenryJames said:

 

Rockland County, home to a large Hasidic community whose members have very low vaccination rates against all sorts of diseases.

It's also where that Orthodox doctor first started treating covid patients with hydroxychloroquine and zinc, and that idea for treatment spread among conservatives across the country. Oh, yeah, they also rioted against covid restrictions and burned masks in the streets.

Point being is that religious zealots, regardless of flavor, keep fucking us over. 

 

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10 minutes ago, HenryJames said:

Duh. It's more profitable to let standards of care slip because what are you gonna do? Get a different employee provided healthcare plan? Nurses are treated like fucking fast food workers but are also entrusted with the health and well-being of our loved ones. No fucking shit they're done getting kicked around by unga bunga redhat chuds just so some insurance fuck can get a fatter margin

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I dunno know who Sarah Jeong is, but she's 100% right. Stay out of the hospital (doesn't matter if for- or non-profit). Super dangerous to be there, especially if you're admitted for more than a day

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21 minutes ago, trauma babe said:

I dunno know who Sarah Jeong is, but she's 100% right. Stay out of the hospital (doesn't matter if for- or non-profit). Super dangerous to be there, especially if you're admitted for more than a day

It's scary, and the nightmare keeps getting worse for the healthcare professionals and patients alike.

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