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Monkeypox 2022 - Stop Sharing Your DIrty Underwear


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1 minute ago, Pancho said:

Apparently the US is going to start dose-splitting so instead of getting the entire vax you’ll get 20% of it injected into the top layer of the skin. 

@trauma babe can maybe explain why that’s better—for now.

It's a measure to extend the coverage with current resources cause the FDA and HHS shit the bed. 

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1 hour ago, Pancho said:

Apparently the US is going to start dose-splitting so instead of getting the entire vax you’ll get 20% of it injected into the top layer of the skin

Screw that. I've got my own system based on the canary in the coal mine. I bought myself a capuchin monkey. He jumps all over my potential mates. I figure if he's okay, I'm okay.

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Lmao, in order to keep access to the vaccine possible, we have to switch to the intradermal administration method. 

Spittin' into the wind imo, but there's some preliminary evidence (not by Jynneos themselves) that you can produce a similar immune response with two intradermal microdoses due to histological differences between subq and intradermal. But I can't source the hard numbers yet.

 

Hope I'm just being a pessimistic bitch about it!

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2 hours ago, Pancho said:

USA! USA!
 

 

Feigl Ding is an alarmist grifter for what it's worth.  Dude has proven to be an absolute joke throughout COVID.  Particularly the past year.    Not saying it's not spreading and increasing but what I think these graphs fail to take into account is the rapid increase in testing capacity over the past 2 months.

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21 hours ago, trauma babe said:

Lmao it's worse.

My clinic will not be doing that. Unless we have vaccine supply cut off to us. It's a fucking stupid idea.

 

7 hours ago, trauma babe said:

Lmao, in order to keep access to the vaccine possible, we have to switch to the intradermal administration method. 

Spittin' into the wind imo, but there's some preliminary evidence (not by Jynneos themselves) that you can produce a similar immune response with two intradermal microdoses due to histological differences between subq and intradermal. But I can't source the hard numbers yet.

 

Hope I'm just being a pessimistic bitch about it!

How it started...how it's going?

I haven't dived into the data on this one, but what is the objection to splitting the doses?

We could have saved a lot of lives during the early phase of the COVID vax roll out by being flexible with second doses, regimen, etc. 

FDA and HHS shit the bed, but if there are strategies to extend the protection, we should consider them fully. 

 

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1 hour ago, Anastasis said:

 

How it started...how it's going?

I haven't dived into the data on this one, but what is the objection to splitting the doses?

We could have saved a lot of lives during the early phase of the COVID vax roll out by being flexible with second doses, regimen, etc. 

FDA and HHS shit the bed, but if there are strategies to extend the protection, we should consider them fully. 

 

My objection is that they haven't presented any data to show that receiving a total of 0.2mL of the vaccine intradermally over a month instead of 1mL subcutaneously over a month has a similar immune response. "It's thought" or "some evidence" is all that's mentioned. I hope to be proved wrong, but a single study from 2015 isn't gonna cut it. I haven't been able to find any more info. Furthermore, giving an intradermal injection is notably trickier than subQ, and when you have such small amounts to begin with, every last fucking molecule matters. 

No one in my org wants to do this, but as we're otherwise going to be cut off from serving our patients, our hand is forced. Other providers and clinics in the area are already turfing their queer patients to us, refusing to even evaluate them for MP. "Let the homos deal with their own" seems to be the prevailing sentiment. 

Lastly, I will repeat that while there are some similarities between the monkeypox and COVID emergencies, especially in how our health agencies refuse to be proactive with these threats, they aren't real analogs. 

 

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27 minutes ago, trauma babe said:

My objection is that they haven't presented any data to show that receiving a total of 0.2mL of the vaccine intradermally over a month instead of 1mL subcutaneously over a month. I hope to be proved wrong, but a single study from 2015 isn't gonna cut it. I haven't been able to find any more info. Furthermore, giving an intradermal injection is notably trickier than subQ, and when you have such small amounts to begin with, every last fucking molecule matters. 

No one in my org wants to do this, but as we're otherwise going to be cut off from serving our patients, our hand is forced. Other providers and clinics in the area are already turfing their queer patients to us, refusing to even evaluate them for MP. "Let the homos deal with their own" seems to be the prevailing sentiment. 

Lastly, I will repeat that while there are some similarities between the monkeypox and COVID emergencies, especially in how our health agencies refuse to be proactive with these threats, they aren't real analogs. 

 

Are you saying that if I'm going to hump a total stranger, I need a full wetsuit and N95 at all times?

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Y'all chill out.  WHO's got this:

The World Health Organization says it's holding an open forum to rename the disease monkeypox, after some critics raised concerns the name could be derogatory or have racist connotations.

They make a good point, but renaming it will make many people think there's a whole NEW disease.  WHO needs to focus on, you know, stopping the disease.

 

https://abcnews.go.com/Health/wireStory/plans-rename-monkeypox-stigmatization-concerns-88305297

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I wish the vax was like the COVID vax in which you could get it anywhere. Seems like with this one you can only get it in the county you live or work in.

 

SF has lots of vaccines with very little lines, but you have to live or work in SF to get it.

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2 minutes ago, Pancho said:

I wish the vax was like the COVID vax in which you could get it anywhere. Seems like with this one you can only get it in the county you live or work in.

 

SF has lots of vaccines with very little lines, but you have to live or work in SF to get it.

The covid vax was most americans' first taste of what socialized medicine could look like, both the good and bad.

The bad was that when demand far outpaced supply, the government had to create priority groups (old immunocompromised, then olds, then medical conditions over 16, then everyone else) and distribution plans.

The good was that eventually we figured it out (massive vaccination drives in stadium parking lots, scheduling websites, deals with CVSes and Walgreenses) and it's the most hassle-free healthcare transaction most people have in their adult lives. No lengthy forms with intrusive questionnaires. No copays. No surprise bills. No bullshit. Just friendly civil servants providing a valuable service to me, paid for with my tax dollars.

Is there any reason why everything else can't be this way?

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On 8/13/2022 at 8:10 AM, Parliament said:

Y'all chill out.  WHO's got this:

The World Health Organization says it's holding an open forum to rename the disease monkeypox, after some critics raised concerns the name could be derogatory or have racist connotations.

They make a good point, but renaming it will make many people think there's a whole NEW disease.  WHO needs to focus on, you know, stopping the disease.

 

https://abcnews.go.com/Health/wireStory/plans-rename-monkeypox-stigmatization-concerns-88305297

Systemic racism is everywhere, pal.  Got to fight it on all fronts.

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On 8/13/2022 at 10:47 AM, chainsaw said:

The covid vax was most americans' first taste of what socialized medicine could look like, both the good and bad.

The bad was that when demand far outpaced supply, the government had to create priority groups (old immunocompromised, then olds, then medical conditions over 16, then everyone else) and distribution plans.

The good was that eventually we figured it out (massive vaccination drives in stadium parking lots, scheduling websites, deals with CVSes and Walgreenses) and it's the most hassle-free healthcare transaction most people have in their adult lives. No lengthy forms with intrusive questionnaires. No copays. No surprise bills. No bullshit. Just friendly civil servants providing a valuable service to me, paid for with my tax dollars.

Is there any reason why everything else can't be this way?

No, it wasn't anything like socialized medicine. The government was willing to take a huge loss in the short-run because COVID. This would not be true with other diseases. Huge losses would not be acceptable so the government would be forced to cut services.

The COVID deal would best be handled by my idea for a plan. Vaccines and check-ups and scheduled diagnostics (mammograms, colonoscopies, etc. would be covered by the government). GP visits would be cash pay. Catastrophic and ER would be insurance based.

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On 8/13/2022 at 10:38 AM, Pancho said:

I wish the vax was like the COVID vax in which you could get it anywhere. Seems like with this one you can only get it in the county you live or work in.

 

SF has lots of vaccines with very little lines, but you have to live or work in SF to get it.

Yeah, I got in relatively easy, but had to call the city to get it scheduled, versus just going online to Walgreens/CVS like my covid shots and boosters.  They had locations all over the city, but you go where they tell you to go. 

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1 hour ago, Bevo said:

No, it wasn't anything like socialized medicine. The government was willing to take a huge loss in the short-run because COVID. This would not be true with other diseases. Huge losses would not be acceptable so the government would be forced to cut services.

The COVID deal would best be handled by my idea for a plan. Vaccines and check-ups and scheduled diagnostics (mammograms, colonoscopies, etc. would be covered by the government). GP visits would be cash pay. Catastrophic and ER would be insurance based.

You sure it's a huge loss? We saved a lot of lives, avoided a lot of costly hospitalizations, a lot of costly treatments for long covid, and got the economy back in gear more quickly.

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30 minutes ago, chainsaw said:

You sure it's a huge loss?

I assume you know we aren't going to pass trillion dollar bills annually to cover costs above our current spending on healthcare. Because that is what we did with COVID. So thinking that it is what socialized medicine would be like is incorrect logic.

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3 minutes ago, Bevo said:

I assume you know we aren't going to pass trillion dollar bills annually to cover costs above our current spending on healthcare. Because that is what we did with COVID. So thinking that it is what socialized medicine would be like is incorrect logic.

I said it was a taste, and it's similar to what they do in Europe. 

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2 minutes ago, chainsaw said:

I said it was a taste, and it's similar to what they do in Europe. 

Only in that it was free at the time of service and the expenses were passed on to future generations. Real socialized medicine would be closer to the DMV style of service.

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2 minutes ago, chainsaw said:

All I'm saying is the monkeypox vaccine should be free and easy to get.

You should have led with that. I don't see monkeypox being different than any other disease that can be prevented through vaccination. And I think all vaccines should be government funded as should wellness checks and standard, scheduled diagnostics like mammography and colorectal cancer screening.

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17 hours ago, chainsaw said:

There are a lot of breeds who like to rub their asses against visitors' legs for some reason. I wouldn't suspect foul play here but it's fun to joke about.

Yeah it’s hilarious until you see how it’s being used by a certain political ideology to further demonize the gays. So fun. 

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https://www.nbcnews.com/news/rcna43484

 

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Since the outset of the global monkeypox outbreak in May, public health and infectious disease experts have told the public that the virus is largely transmitting through skin-to-skin contact, in particular during sex between men. 

Now, however, an expanding cadre of experts has come to believe that sex between men itself — both anal as well as oral intercourse — is likely the main driver of global monkeypox transmission. The skin contact that comes with sex, these experts say, is probably much less of a risk factor.

In recent weeks, a growing body of scientific evidence — including a trio of studies published in peer-reviewed journals, as well as reports from national, regional and global health authorities — has suggested that experts may have framed monkeypox’s typical transmission route precisely backward.  
 

Reconceiving the primary risk factors for transmission is crucial because of how it may affect guidance on reducing the risk of infection, including the question of whether demanding that people with the virus self-isolate has any substantial impact on transmission.

“A growing body of evidence supports that sexual transmission, particularly through seminal fluids, is occurring with the current MPX outbreak,” said Dr. Aniruddha Hazra, medical director of the University of Chicago Sexual Wellness Clinic, referring to monkeypox and to recent studies that found the virus in semen.

Consequently, scientists told NBC News that the Centers for Disease Control and Prevention and other public health authorities should update their monkeypox communication strategies to more strongly emphasize the centrality of intercourse among gay and bisexual men, who comprise nearly all U.S. cases, to the virus’ spread.

On Aug. 14, Dr. Jeffrey Klausner, an infectious disease physician at the University of Southern California, and Dr. Lao-Tzu Allan-Blitz, a resident physician in global health at Brigham and Women’s Hospital in Boston, published an essay on Medium in which they reviewed the science supporting the argument that during the current outbreak, monkeypox is largely transmitting through anal and oral intercourse between men.

“It looks very clear to us that this is an infection that is transmitting sexually the vast majority of the time,” Allan-Blitz said.

This debate, however, is far from settled.

Dr. Rosamund Lewis, technical lead for monkeypox at the World Health Organization, told NBC News it was “unfortunate but true” that “we don’t know yet” whether the virus is predominantly transmitted through intercourse.

“Completely reading the situation as uniquely due to anal or oral sex is highly likely to be overreach,” she said. “The correlation may appear to be strong, but that does not explain the whole picture of disease caused by this virus. So we need to keep an open mind.” 

Some experts in infectious disease see evidence supporting the argument that monkeypox at least transmits more readily through intercourse.

“At this point,” said Dr. Paul Adamson, an infectious disease specialist at the UCLA School of Medicine, “I’m not sure we can say it is primarily the sexual transmission and not the skin-to-skin contact that also occurs during sex that is contributing to the most transmission during this current outbreak. However, emerging data seem to suggest that monkeypox might be more efficiently transmitted sexually.”

Parsing the evidence

In an interview, Klausner, who has submitted a version of his and Allan-Blitz’s essay to a scientific journal for publication, distilled the evidence that he said supports the hypothesis that sex itself fuels the global outbreak into four major points. 

First, he noted that, according to the WHO, more than three quarters of global monkeypox cases are among men 18 to 44 years old. This is a typical age breakdown for diagnoses of sexually transmitted infections among gay and bisexual men, he said. What’s more, in recent studies of pooled monkeypox cases among this demographic, 17% to 32% of those diagnosed with the virus received a sexually transmitted infection (STI) diagnosis at the same time.

Second, during the global outbreak, atypical to what has historically been seen in the 11 African nations where the virus has become endemic since first being identified in humans in 1970, monkeypox lesions have in the majority of cases occurred in men’s genital and anorectal areas. This, experts told NBC News, suggests that these were the sites where the virus first passed into the body.

In a study of 197 monkeypox cases in London men published July 28 in The BMJ, the British Medical Association’s journal, researchers found that 56% had lesions in the genital area and 42% had them in their anorectal regions. And in a study published July 21 in The New England Journal of Medicine, a global team of researchers pooled 538 monkeypox cases — also all in men — from around the world and found that 73% had lesions in the genital or anorectal areas. 

Third, researchers have found monkeypox in semen and have been able to culture that virus, which suggests it could transmit through ejaculation. Also, the authors of two recent studies have detected the virus after taking anal swabs among men who had monkeypox but were asymptomatic, which indicates that the virus might transmit from the anorectal area during anal intercourse before people develop symptoms. Experts say more research is needed on both these fronts.

Referring to bodily fluids such as semen, vaginal fluids and blood, the WHO’s Lewis said, “Research is underway to find out more about whether people can spread monkeypox through the exchange of these fluids during and after symptomatic infection.”

Finally, Klausner noted that scientists have identified an association between specific sexual acts and the location of monkeypox lesions. 

 

 

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On 8/15/2022 at 1:49 PM, sidis said:

this monkeypox thing is making me nervous about getting lap dances in vegas with my wife next month...

https://www.cnn.com/2022/08/17/health/monkeypox-case-nonsexual-transmission/index.html
 

Quote

A man noticed his first lesion and subsequently developed a rash about two weeks after attending a "large, crowded outdoor event at which he had close contact with others, including close dancing, for a few hours," according to researchers from Stanford University School of Medicine. He tested positive for monkeypox after seeking care at an emergency department about a week later.

The patient's "primary risk factor was close, nonsexual contact with numerous unknown persons at a crowded outdoor event," the researchers wrote, and the case "highlights the potential for spread at such gatherings, which may have implications for epidemic control."

So umm, anybody here catches it, just say you were dancing at a crowded outdoors event,

Suspicious Monkey GIF by MOODMAN

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