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JohnLocke

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Everything posted by JohnLocke

  1. Ok, I'll bite. There is not RCT results available that A) use hydroxychloriquine with zinc and azithromycin and B) are given early as an outpatient and C) have a large enough sample size of high risk patients to yield statistically significant results. I tend to be influenced when I see dishonesty and what I have seen is HCQ being discarded as a treatment based on the fact A) it doesn't work well on very sick patients and B) statistically insignificant results, although positive, and needing larger sample sizes, are reported in the mainstream media as if they were negative results. The 2nd layer of dishonesty has been the attack on the safety of HCQ, a widely used and well understood drug that is OTC in much of the world. In Harvey Risch's words: The combination of hydroxychloroquine and azithromycin has been used for decades in hundreds of thousands of people with rheumatoid arthritis. There is a concern that these medications do change the heart pacing a little and could cause cardiac arrhythmias. However, these arrhythmias are still very rare in people using these medications. People who already have heart arrhythmias or are predisposed to them or have family histories of them should discuss this with their health care providers and see if using hydroxychloroquine plus doxycycline or some other medications would be a better choice. There is almost no downside to trying this drug if you are at high risk. In Dr. Risch's words again: Hydroxychloroquine alone is not the whole story. It needs to be combined with azithromycin or doxycycline and probably with zinc to make it most effective. The game changer is to aggressively treat people as soon as possible, before they are hospitalized, to keep them from becoming hospitalized in the first place. Hydroxychloroquine plus the other medications is what we know about now. In a few months we may have data on other medications that also work. We just have to start with something now. The medical profession has been slow to act on data that is not based on RCT's. Shamefully so, when the data can be conclusive in and of itself. I point again to the rather shameful behavior of the medical profession in adopting antibiotics to treat ulcers as exhibit A. When you are in the middle of a pandemic, you don't have time for RCT results. However, there is a huge mass of data available to sift through that is significant. I give the CDC an F for being prepared and able to do the heavy lifting in that regard. We'll have much better data in six months. And hopefully, better treatment options to go along with a vaccine.
  2. You are johnny on the spot with this info.
  3. Yeah, that's probably what I'd do too. You guys could home school him pretty easy yourself for Kindergarten if he doesn't have a late spring or summer birthday, and just put him in first grade next year. Sounds like more of a daycare issue.
  4. Well, insensitive remarks aside, I'd give AISD a chance if you can. You may be pleasantly surprised. And if after a few months, you aren't happy, you can put him in private school then. And if you put him in this year, he'll want to stay next year 'cause that's where all his friends will be.
  5. You could get an out of work stripper to watch him while he does virtual school. I'll bet he would learn a lot.
  6. Why, yes, of course we are. Why wouldn't we? How else can we come in years late with double the price?
  7. I'm not interested in it as an investment. Just pointing out the treatment is generating some buzz, and people are putting money on it. It hasn't been tested in many patients, but so far the treatment has had remarkable success.
  8. Leave it to Austin to sink a fortune into subways when we are on the cusp of driverless taxis and buses. I sure hope this corrupt mega money sinkhole, which will screw up transportation for decades, does not pass. But it's Austin, so it probably will.
  9. This guy makes sense to me, anyway: https://www.washingtonexaminer.com/opinion/hydroxychloroquine-works-in-high-risk-patients-and-saying-otherwise-is-dangerous This company's penny stock up 10x due to good results in seriously ill patients: RADNOR, Pa. and GENEVA, Aug. 2, 2020 /PRNewswire/ -- NeuroRx, Inc. and Relief Therapeutics Holdings AG (SIX:RLF, OTC:RLFTF) "Relief" today announced that RLF-100 (aviptadil) showed rapid recovery from respiratory failure in the most critically ill patients with COVID-19. At the same time, independent researchers have reported that aviptadil blocked replication of the SARS coronavirus in human lung cells and monocytes. RLF-100 has been granted Fast Track designation by FDA and is being developed as a Material Threat Medical Countermeasure in cooperation with the National Institutes of Health and other federal agencies. Further research will be conducted. The first report of rapid clinical recovery under emergency use IND was posted by doctors from Houston Methodist Hospital. The report describes a 54-year-old man who developed COVID-19 while being treated for rejection of a double lung transplant and who came off a ventilator within four days.1 Similar results were subsequently seen in more than 15 patients treated under emergency use IND and an FDA expanded access protocol which is open to patients too ill to be admitted to the ongoing Phase 2/3 FDA trial. https://seekingalpha.com/pr/17955298-rlfminus-100-aviptadil-clinical-trial-showed-rapid-recovery-from-respiratory-failure-and
  10. Aside from some linemen, the likelihood is that 2 specific players would enter a 6-foot radius of each other for < 2 min/game. They must have done that study focusing exclusively on our defensive backs last year....
  11. So, the season's over. Blame the scientists that say it's medically unsafe. When the dust settles, no bureaucrats will take a stand against that. Sliver lining: Lack of revenue is going to hurt a lot of programs badly. Despite what is sure to be a lot of whining from the athletic department asking for donations, UT is in a much better position than most to ride it out.
  12. You do realize he is simply summarizing the research of others. I don't know if what he is saying is true or not, but the t-cell immunity theory does help explain why the pandemic is basically over in Sweden:
  13. Public education has been a dumpster fire in America for a long time. "Normal" public education is an embarrassment. I hear this a lot but I don't see it. The formula hasn't changed in 75 years. If the parents care, the kid cares. And if the kid doesn't care, then everyone is wasting their time. Kids get a good education if they want it. My biggest complaint when my kids were in public high school is they had too much homework all the time. Nothing has really changed, except schools today make a superhuman effort to get marginal kids who don't care to pass the required testing. What purpose that really serves is a bit of a mystery.
  14. The extra 10 minutes likely isn't going to change much instruction wise. Extracurriculars will have to wait an extra ten minutes before starting after school. This is basically the locals working around the TEA.
  15. What has changed in the board approved calendar? The school year start date for students has been revised to September 8, 2020, and the end date has been revised to June 3 with additional instructional minutes added per day to ensure students receive the required amount of instructional time.
  16. College football fans everywhere: "That's surprising. Good basketball, but I didn't realize they had a football team."
  17. Seems likely, but less because AISD is doing it, and more because they weren't planning on having kids on campus Aug. 18th.
  18. Damn, that's frightening, and a pretty good argument against opening high schools right now.
  19. I honestly have a lot of respect for the medical profession. They perform near miracles on a daily basis. But to say they can be hard headed on occasion is an understatement. When an Australian doctor figured out that antibiotics cured ulcers in almost 100% of his patients, and he published a paper to that effect in 1985, it took TEN YEARS for the medical community to accept it. What is surprising given the low cost and safety of the treatment, and the fact that virtually 100% of patients were being cured, is that very few doctors just tried it. Thousands, maybe hundreds of thousands, of patients suffered and some died while this treatment was being proven in RCT's. The incentives for doctors to try unproven treatments is very low, and I can understand that. HCQ is particularly tough, given that most patients will recover without it, and some may die with it. It's very hard to tease out the real signal from all the noise. However, it makes sense to me as a patient (without heart issues) to try HCQ plus zinc as an outpatient when covid is first suspected. Very low risk, and possible to probable benefit, and there is nothing else anyway. If I have to play Russian roulette, I'd like as few bullets in the chamber as possible. From a doctor's perspective prescribing it, it's all risk and no benefit. You could get sued if the patient has a heart problem, and there is no upside to them recovering without hospitalization, which they will likely do anyway.
  20. Schools will be lucky to get 75% attendance. This is going to be a huge problem for schools.
  21. Exactly. This is way past the last minute. Explain how social distancing works without limiting the numbers on campus. What a CF.
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