Short answer: maybe
They would likely put you back on the drip. Or, if available, a pill for “maintenance chemo”. Or put you into a trial for experimental drugs if one is available and you qualify.
Long answer: there could be multiple options
My experience was surgery, heal for a month, then do chemo and radiation simultaneously, then I was clear for a year.
When it came back in my liver (colorectal cancer that was metastatic to my lymph and liver), they switched to a different chemo. Once that cleared out the tumors, I was clear for a year.
It came back in my liver and one lymph node by my aorta.
Tumor board and liver board argued about what to do. Medical oncologist wanted to try another chemo. Surgeon said “I don’t want to try surgery on him after you have had him”. Radiation oncologist said “make a decision, I’ll jump in wherever you need me”.
We ended up with liver resection and lymph removal and intra-operative radiation by my aorta where that lymph node was removed.
I have been clear ever since but it was not easy. Or cheap.
My oncologist that referred me to M.D. Anderson had even told me she would like to consider chemo before doing something as aggressive as they were suggesting. But then she thought about it and said “you are young, you can handle all of this”.
If radiation doesn’t work, be prepared for some way-outside-the-box thinking. They don’t like to lose battles and they will try to come up with something to kill that cancer and not take you with it in the process.