I never had cisplatin, but I had oxaliplatin. Not sure how similar their side effects are but I didn’t have tinnitus that I can recall.
What seems to have prevented me from ending up with most side effects, particularly the peripheral neuropathy in hands and feet, was lots of L-Glutamine.
Long story, but my wife had done research to find any supplementation that would help fight the cancer, or would support my body against the treatment.
A yogurt smoothie with fruit and Jay Robb brand protein powder every day might have been the key. More on that in a minute.
The protein powder (egg white or whey, doesn’t matter to me) has over 4000mg of an amino acid called L-Glutamine. The original plan was to use that to fight tumor growth because a supplement we had wanted (but was back ordered) claimed to slow or stop tumor growth due to its use of glutathione. Your liver turns certain amino acids into glutathione. Thats why we went with this particular protein powder. That, and it doesn’t taste like chalk like most of them.
At one point my oncologist at Methodist in Houston said “I don’t know how you are doing what you are doing, but keep doing it” because things were going really well for me.
At some point I ended up seeing another oncologist in another location. I showed her the write-up from the supplement company about the purported effects of the glutathione supplement. She said “yeah, I know you want to believe it, but it’s one study, by a company that sells the supplement. Show me three other studies that were able to duplicate those results and then I’ll be on board.”
Ouch.
Fast forward a few years. I’m at her clinic to get routine blood work and get my port flushed and she sees me and says “Hey! Hey! When you are done getting your port flushed I need to talk to you! Go to an exam room!!!”
I had been in remission a few years (for the third time) by this point.
She comes into the exam room with my giant-ass file. She pulls out the mailer from the supplement company that I had brought her. It was tucked in there.
She says “You remember how you wanted this supplement with the glutathione to stop tumor growth? And how you haven’t had neuropathy like my other patients getting treated for colorectal cancer?”
“The ASCO (American Society of Clinical Oncologists) conference just happened and they released all of their info that was shared there. One study that was shared showed the effects of L-Glutamine supplementation in patients using platinum-based drugs to prevent neuropathy! You were taking that protein powder for another reason but it worked to accomplish something else.”
She was pumped and planned to share this info with her patients going forward.
I can only share what worked for me. Maybe that amino acid did the job. Maybe there is more to it than that. The body is complex and we all tolerate and metabolize things a little differently.
However, there is this: https://www.webmd.com/vitamins/ai/ingredientmono-717/glutathione?ref=clips2click.com
Being so far along in your treatment, it might not be helpful. I don’t know if you have to start ingesting this stuff before starting and keep at it or if it will help after you are already having symptoms or what. I don’t have that kind of info.
If it’s me, I’m buying some yogurt and protein and starting it anyway, but I can only go my my own experience.