Astros still have to play the Mariners and Rangers 3 times each, and they have to play each other 7 of the last 10 games of the season. I think that they will beat each other up, and as long as the Astros can go 2-1 in those series, they should be good to at least make the wild card. The schedule coming up has a lot of easy games, Tigers, Padres, As and the Royals twice, so there is plenty of opportunity for this team to win a lot of games and the division. It's going to be a wild ride all the way to the end, but that likely means they won't be able to rest anyone important for the last few games.
In the past, the Astros haven't had anyone close to taking the division for the last 1-2 weeks of the season, and it has allowed them to go into the playoffs well rested, but that probably won't happen this year. That could hurt them, but it also makes winning the division more important to get the Bye and have a much better pitching rotation to start the playoffs. Philly made the World Series last year being a 6th seed, so if they get a Wild Card it's not the end of the line, but winning the division would be pretty sweet for a lot of reasons, and to fuck over the Rangers and Mariners.