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Chopper

Certifiably Surly
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Everything posted by Chopper

  1. Dementia Don is losing the war on woke.
  2. Just a Kavanaugh Stop. Nothing to see here.
  3. city of Austin gets brought up in one of the dumbest possible ways. Trump doesn't disappoint, sputters like Miss S Carolina.
  4. The man was basically shot with his own gun this dude has the crim complaint details
  5. corporate press release: The discoveries of Dr. Ramsdell and others have deepened our understanding of autoimmune diseases and the important role of Tregs, which prevent immune cells from attacking a patient’s own body SOUTH SAN FRANCISCO & SEATTLE – October 6, 2025 – Sonoma Biotherapeutics, Inc., a clinical-stage biotechnology company developing engineered regulatory T cell (Treg) therapies for autoimmune and inflammatory diseases, is honored to announce that Fred Ramsdell, PhD, Sonoma Biotherapeutics co-founder, past Chief Scientific Officer (CSO), and current chair of the Scientific Advisory Board, was named a winner of the 2025 Nobel Prize in Physiology or Medicine. “Congratulations to Fred Ramsdell, co-founder of SonomaBio, and a valued friend and colleague. Like many great scientists, Fred spent years working behind the scenes to identify the gene that caused devastating systemic autoimmune diseases in a little-known strain of mice,” said Jeff Bluestone, PhD, Chief Executive Officer and President. “The discovery of the gene, FOXP3, changed our understanding of peripheral tolerance and led to a new field of immunotherapy.” “SonomaBio is proud to have had Fred as our previous Chief Scientific Officer and current advisor. His seminal work—together with Alexander Rudensky, PhD, co-founder and scientific advisor to SonomaBio—have been the guiding light for our development of Treg cell therapies that we are confident will change the world of immunotherapy to treat the most difficult autoimmune diseases,” continued Bluestone. Dr. Fred Ramsdell’s work in the discovery of the gene, FOXP3, and its role in Treg development changed the field of immunology. He is a veteran biotechnology leader in immunology with nearly three decades of experience and was named along with Dr. Rudensky, the 2017 Crafoord Prize – Polyarthritis. A co-founder of Sonoma Biotherapeutics, Dr. Ramsdell was the former CSO and current Scientific Advisory Board Chair of the Company. Dr. Ramsdell earned his doctoral degree in microbiology and immunology from the University of California, Los Angeles and holds a bachelor’s degree in biochemistry and cell biology from the University of California, San Diego. Following a fellowship at the NIH, Dr. Ramsdell joined Immunex studying T cell activation and tolerance, with a focus on gene discovery and functional characterization. He later joined Darwin Molecular (which was later acquired by Celltech R&D) to establish the immunology program. Amongst other programs, he led the team that discovered and characterized FOXP3, a gene critical to the function of regulatory T cells. Dr. Ramsdell joined ZymoGenetics in 2004, where he led teams studying novel proteins with potential regulatory activity in lymphoid cells. In 2008, Novo Nordisk brought on Dr. Ramsdell to help establish the company’s new Inflammation Research Center in Seattle and lead the Immunobiology group. Prior to SonomaBio, Dr. Ramsdell was the CSO at the Parker Institute for Cancer Immunotherapy (PICI) where he helped to build and advance multiple research programs from the inception of the Institute. About Sonoma Biotherapeutics Sonoma Biotherapeutics is a clinical-stage biotechnology company developing engineered regulatory T cell (Treg) therapies to treat serious autoimmune and inflammatory diseases by restoring balance to the immune system. Founded by pioneers in Treg biology and cell therapy, the company is employing proprietary platform technologies and approaches to develop a new generation of targeted and durable Treg cell therapies.
  6. Yeah I was going there but then I saw his wife was with him on the hike.
  7. "Epstein files? Never heard of 'em." "Project 2025? What's that?" "The Constitution? Never read it." "Bad Bunny? Well lemme tell you something..." The Bad Bunny thing is about their anger that the NFL didn't accede to the magat culture preferences.
  8. California man, UCLA, UCSD grad - Dr Ramsdell, whose phone had been on airplane mode when the Nobel committee tried to call him, told the BBC's Newshour Programme that his first response when his wife said, "You've won the Nobel prize" was: "I did not." To which Ms O'Neill replied that she had 200 text messages that suggested he had. While the committee was trying to reach him, he "was living his best life and was off the grid on a preplanned hiking trip," a spokesperson for his lab, Sonoma Biotherapeutics, said.
  9. This is the thing about being Jewish. As someone put it better than I can, legal immigration and humane treatment of individuals should be part of your social understanding. I have some magat family and "it makes me ragey."
  10. Thanks for the update. And who doesn't have a playlist with songs about fire?
  11. pro-DEI when it serves THEM ACAB "ASSIGNED COP AT BIRTH"
  12. LA Times https://archive.is/netmw Apparently the guy is an uber driver from FL but was shooting off fireworks near Topanga Canyon (Skull Rock Trail) on New Year's Eve. Not all details are public yet.
  13. Prospect published a super interesting article about agricultural workers and an odd, hypocritical Federal Rules change just proposed by the Administration. The administration claims there's a crisis in farm labor and wants to bring in more immigrant farm workers by cutting wages paid to legal immigrant farm workers, and allow the ag industry to deduct the cost of housing from paychecks (just like human traffickers do) It's about using immigration to increase the profits of agribusiness. https://prospect.org/politics/trump-labor-department-immigration-ICE-food-crisis/ the tldr
  14. ‪@sarahposner.bsky.social‬ Local El Paso coverage has much more detail on the package of information presented to Pope Leo, including the video: "Together, let us be a church that refuses to abandon our people, one that walks in faith, justice, and love" elpasomatters.org/2025/10/08/e... In Vatican meeting with El Pasoans, Pope Leo XIV offers support to migrants facing deportation - El Paso Matters During a Vatican meeting, Pope Leo XIV expressed solidarity with migrants after hearing firsthand accounts gathered by El Paso’s Hope Border Institute and La Mujer Obrera about the human toll of U.S. ... elpasomatters.org
  15. Yes but the FBI has the same info as the DA and the regarded FBI director would have leaked anything helpful to the fascist narrative. Therefore, one can conclude...
  16. We were there last December and it was great. But it's just closed for a full reno until 2030. Per their website they're reopening for two days (Oct 24 and 25) for a celebration. Tickets are required.
  17. Not only that they're trying to elicit a violent reaction from normies, so they can use it as justification for a more violent crackdown. They're building up the size of ICE to one of the world's largest militaries for a reason.
  18. ha yes I should've been more specific and will edit. I'm not sure he stopped because he realized how stupid he sounded.
  19. Kimmel last night. He still knows what to talk about.
  20. Asha's take. I'm not sure her theory about why he stopped talking is correct.
  21. The Democrats won an election in Fairbanks last night. Molly O'Neal ousted a Republican incumbent. In a shocking move, the R candidate conceded gracefully. Bolt Magazine described the incumbent as "a Trumpian, conservative mayor who has fought protections for LGBTQ+ residents and whose comments drew condemnation this year from Alaska Natives." Newsweek: "Mayoral elections in Fairbanks are nonpartisan, and the ballot does not list party affiliations next to candidates’ names. However, Republicans have held the mayoralty in Fairbanks for nearly a decade. Pruhs, a conservative backed by local Republicans, was elected mayor in 2022. O’Neall, the presiding officer of the Fairbanks North Star Borough Assembly, was endorsed by the Alaska Democratic Party." “The race is over. Mindy O’Neall won. A few votes yet to be counted, but I'm down by 250 votes. The voters have spoken,” Pruhs told Alaska’s News Source. Pruhs blamed low voter turnout and O’Neall having the support of the state Democratic Party for his defeat. “It was a perfect storm for her to take the seat, and she did that. So congratulations to Mindy O’Neall,” he said."
  22. Theoretically yes. The Chair is supposed to bang the gavel to bring order. But the Chair is not just uncooperative, they're basically aiding and abetting. I'd really love to hear from a psychologist or someone with a similar profession about the best way for a Senator to treat a witness who behaves like that. It seemed like Schiff did the best job but I'm wondering if they mocked her, how they might have gone. Try some other approaches, maybe. We see the sartorial senators trying to be dignified but confronted by a wild squealing hyena. Are they going to be polite or are they going to get a figurative rope around that hyena's throat and go to work.
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