Jump to content

Anastasis

Certifiably Surly
  • Posts

    31324
  • Joined

  • Days Won

    8

Everything posted by Anastasis

  1. Sounds like bizarro world CR.
  2. Does your quote function not work?
  3. lol. You really this on tilt about the tapper book? Like do you feel really this bad for arguing against obvious reality? Let me ask you a question. How much of your daily media consumption is Twitter and blue sky? Trump dissembling and quoting wholesale gas prices. Are you shocked? I ain’t. Like no self awareness at all.
  4. Agree. The booster recommendations have been outkicking the evidence coverage. This brings us more in line with the recs in the rest of the developed world.
  5. On topic of the thread. More at the link that gets into the study design recommendations and other considerations. https://www.nejm.org/doi/full/10.1056/NEJMsb2506929#f1 An Evidence-Based Approach to Covid-19 Vaccination Authors: Vinay Prasad, M.D., M.P.H., and Martin A. Makary, M.D., M.P.H.Author Info & Affiliations Published May 20, 2025 Over the past 5 years, the United States has moved toward an annual Covid-19 booster program. Each fall, Covid-19 booster shots are developed, alongside seasonal influenza vaccines, and are recommended for every American. As compared with vaccination policies in all European nations, the U.S. policy has been the most aggressive (see Figure 1).1 While all other high-income nations confine vaccine recommendations to older adults (typically those older than 65 years of age), or those at high risk for severe Covid-19, the United States has adopted a one-size-fits-all regulatory framework and has granted broad marketing authorization to all Americans over the age of 6 months.1 The U.S. policy has sometimes been justified by arguing that the American people are not sophisticated enough to understand age- and risk-based recommendations.2 We reject this view. Although the rapid development of multiple Covid-19 vaccines in 2020 represents a major scientific, medical, and regulatory accomplishment,3 the benefit of repeat dosing — particularly among low-risk persons who may have previously received multiple doses of Covid-19 vaccines, had multiple Covid-19 infections, or both — is uncertain. The American people, along with many health care providers, remain unconvinced. Over the past two seasons, uptake of the annual Covid-19 booster has been poor, according to the Centers for Disease Control and Prevention (CDC). Less than 25% of Americans received boosters each year, ranging from less than 10% of children younger than 12 years of age in the 2024–2025 season to 50% of adults over 75 years old.4 Even health care workers remain hesitant, with less than one third participating in the 2023–2024 fall booster program.5 There may even be a ripple effect: public trust in vaccination in general has declined,6 resulting in a reluctance to vaccinate that is affecting even vital immunization programs such as that for measles–mumps–rubella (MMR) vaccination, which has been clearly established as safe and highly effective. In recent years, reduced MMR vaccination rates have been a growing concern and have contributed to serious illness and deaths from measles. Against this context, the Food and Drug Administration (FDA) seeks to provide guidance and foster evidence generation. Moving forward, the FDA will adopt the following Covid-19 vaccination regulatory framework: On the basis of immunogenicity — proof that a vaccine can generate antibody titers in people — the FDA anticipates that it will be able to make favorable benefit–risk findings for adults over the age of 65 years and for all persons above the age of 6 months with one or more risk factors that put them at high risk for severe Covid-19 outcomes, as described by the CDC (Figure 2). For all healthy persons — those with no risk factors for severe Covid-19 — between the ages of 6 months and 64 years, the FDA anticipates the need for randomized, controlled trial data evaluating clinical outcomes before Biologics License Applications can be granted. Insofar as possible, when approving a Covid-19 vaccine for high-risk groups, the FDA will encourage manufacturers to conduct randomized, controlled trials in the population of healthy adults as part of their postmarketing commitment.
  6. LOL. Gleason score 9/10. Be serious guys.
  7. I understand. This board has evolved away from real talk.
  8. Maybe not everything that happens in the world is about us and our political dysfunction?
  9. How do you feel about personality disorders?
  10. And nobody should brush off personality disorders. Not sure where you got that notion from, but certainly not from anything I posted.
  11. Trump has NPD. This is not a particularly controversial take. Probably the most malignant presentation of NPD ever in a public official.
  12. I see that we have entered the "bang on the table and yell" phase of the exchange. You are going to have to come to grips with what happened. There will be stages of grief that you have to work through. Its all part of the process if you want things to get better.
  13. You are clowning yourself. If y'all can't even come to grips with how you got played by the Biden admi, the DNC, and the media, it does not portend well for the future.
  14. All deflection from the fact that we had a clearly declined demented individual in the office, and the DNC and his inner circle and the media all ran cover for it. Whataboutism is cool I guess when it is based on delusions and strawmanning. I voted Amash in 2020, and voted to go deer hunting in 2024 ftr.
  15. I haven't voted for any of these clowns. Just keep blindly pulling the lever for whatever the DNC busts in the back of your throat though. I also clowned on the people that use their academic titles in their social media handles.
  16. We had a clearly mentally declined, demented individual in the role of President. His inner circle ran cover for that. The media ran cover for that. Now they sell books about it. This is all totally normal and cool. Because orange man bad.
  17. Of course. But you told me that I have "no fucking clue" what I am talking about. I don't really care what sort of academic dick measuring contests take place in your industry. People with PhDs that roll around introducing themselves as Dr so and so outside of academic settings are generally pretentious little twats. And that extends to physicians to a certain extent as well, outside of clinical or academic settings.
  18. Literally everyone I work with, with rare exception, has at least one doctorate. Some clinical doctorates as well, MD, etc. And double dipping. Rare for any of them to introduce themselves as Dr. so and so or use their academic titles in normal professional exchanges. To the extent that they do, more typical for the physicians. Academic settings are of course different. And certainly clinical situations.
  19. What about Trump??!!? Trump has NPD. Everyone with two eyes, no pdh or md required, knows that. Everyone in his inner circle knows that. Sorry you have to hear this from me. The DNC and the media shit the bed with Biden 2024 guys. It will be ok. A little self reflection might be in order, but you aren't gonna want to hear that from me. I get it.
  20. I mean, I guess enjoy discussing the "nuances" of age specific incidence rates of dementia with Willfully buddy.
  21. You just posted Rebekah Jones’ substack.
  22. Every one with two eyes, no phd or md required, knew that biden was mentally declined for a long time. Everyone in the inner circle certainly knew it. Everyone that has dealt with dementia and the aging process with family personally knows this. Again, no phd in ed psych or whatever required. They covered it up. It's pretty obvious. I would wager a large amount that they had indications of the prostate cancer over a year ago as well. No reason to believe that they did not cover that up as well. Sorry that you guys have to hear this shit from me.
  23. You you should either know that you are wrong, or at least know that you are kicking around in the shallow end of the pool.
  24. I can't even believe that I am entertaining the notion of getting involved in a conversation with an aggie of how people with academic doctorates refer to themselves in real life situations compared to physician's use of the term doctor.
×
×
  • Create New...