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atomheartbevo

Certifiably Surly
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Everything posted by atomheartbevo

  1. Trump/Musk/RFK Jr shut down a big contract with Moderna for a bird-flu vaccine https://news.modernatx.com/news/news-details/2025/Moderna-Announces-Update-on-Investigational-Pandemic-Influenza-Program-/default.aspx The Company had previously expected to advance the program to late-stage development with the U.S. Department of Health and Human Services (HHS); however, today Moderna received notice that HHS will terminate the award for the late-stage development and right to purchase pre-pandemic influenza vaccines. "While the termination of funding from HHS adds uncertainty, we are pleased by the robust immune response and safety profile observed in this interim analysis of the Phase 1/2 study of our H5 avian flu vaccine and we will explore alternative paths forward for the program," said Stéphane Bancel, Chief Executive Officer of Moderna. "These clinical data in pandemic influenza underscore the critical role mRNA technology has played as a countermeasure to emerging health threats." The Phase 1/2 study evaluated a two-dose regimen of Moderna's investigational avian influenza vaccine. mRNA-1018 demonstrated a rapid, potent and durable immune response. At baseline, pre-existing immunity was minimal, with only 2.1% of participants showing hemagglutination inhibition (HAI) antibody titers ≥1:40, an HAI titer considered to correlate with protection. At Day 43, three weeks after the second vaccination, 97.8% of participants achieved titers ≥1:40 with a 44.5-fold increase of titers from baseline. The investigational vaccine was generally well-tolerated, with no dose-limiting tolerability concerns observed. Most solicited adverse reactions were Grade 1 or 2 and did not increase significantly with number of doses or between first and second doses. Further data is expected to be submitted for presentation at an upcoming scientific meeting. Moderna will explore alternatives for late-stage development and manufacturing of the H5 program consistent with the Company's strategic commitment to pandemic preparedness.
  2. NASA's acceptable risk thresholds will change - Musk got some of his people into top positions within NASA. DOGE was never about government efficiency, it was about shutting down investigations into his companies while at the same time trying to get his companies in to take over a lot of government stuff or take contracts from other companies.
  3. Meanwhile, how many of us guys on Surly were sweating it when we had penis reduction surgeries.
  4. Why not, it's apparently how RFK Jr is running things. RFK Jr.'s 'Make America Healthy Again' Report Cites Fake Studies
  5. Well, if you check the Star Wars Nerds threads in the movie forum, you'll find people using AI to create trailers for movies about Luke Skywalker and Yoda making out and having babies. And it's the culmination of these companies trying to push AI to the masses, in addition to ridiculous wastes of energy used to generate stupid shit.
  6. Damn, Dana Delany in that second episode. And William Shatner pushing his Tekwar books. It's a trip back to the 90s, that's for damn sure.
  7. Is the forcefield going to hold?
  8. Was about to suggest Caligula, but that's one to watch with your wife, and you all have probably seen it.
  9. “safe” I notice Musk refuses to fly on his own rockets.
  10. Or some Marion Morrison movies.
  11. Hopefully you don't get "Flowers on the Wall" stuck in your head again.
  12. So, in the shower on our phones generating deep fake porn with Sela Ward and myself in real-time?
  13. @Pato del Muerto when I first heard that song in the late 70s or early 80s on oldies radio, it was less than 25 years old. For reference, that would be like my kid hearing Baby One More Time by Britney Spears or Livin La Vida Loca by Ricky Martin.
  14. Best we can do is park a cell over 45th and Shoal Creek and try and have Shoal Creek overflow and top the 38th Street bridge.
  15. I wish Lobo/YGIFS were here to see this. I want to believe that Musk stole his wife (and she has to be very appealing to him, having birthed 3 kids in under 5 years) because the irony would be just off-the-charts and Miller was already a hateful little prick, so I'd imagine this would freak him the fuck out.
  16. I know half-a-dozen people who died from covid over the span of 2 years and it's probably a bias of some sort because I'm pushing 50 and so my aunts/uncles/older in-laws/friends' parents are all in their 70s-90s so I knew a shitload of senior citizens/elderly. But on the isolation thing, help me out here, I'm not trying to be a dick or insensitive, but when you say "isolation" what are you talking about? We were never stuck in our homes like the Chinese were and I'm always curious when I hear people talk about "isolation". In my case, my family, weather permitting, were out walking or biking every single day, walking around parks or just down the creek, we were driving out to pick up food at various restaurants and grocery stores (whose employees were obviously coming in), we were getting stuff delivered from Amazon, Walmart, etc. I was on Zoom 2-3 hours or more a day, my kids were on Zoom 2-3 hours a day with classmates. We had multiple evenings during the week where we were on Zoom with my wife's Sunday school group playing games or just shooting the shit. I had 3 different zoom calls setup every week with various parts of our family where we'd have anywhere from 5-10 family members on a call, plus I had a regular zoom call going with about 20 high school friends (and prior to that our interaction was the occasional text or facebook message or like). In fact, I spoke with some family and friends far, far more during COVID than I did before or after. I mean I had a calendar on the wall listing all of different things we had going on every single day or night in terms of zoom or phone calls or online gaming with friends (Roll20.net was amazing). So when I hear people talk about "isolation" during COVID, I'm always curious, because I was arguably more connected with family/friends and some people I did some freelance projects with during COVID than I ever have been before or after. In fact, our older relatives that we rarely talked to, we were talking to every week or two for an hour or more, and checking in on them, etc. Now it drove me crazy that my kids and wife were home all the time, but that was just a lot more family time than anticipated. I will say it did affect kids in school at certain ages - that needs to be studied, although many have seemed to have bounced back or even forgotten about it (depends on the age of the kids). What I'm getting at, is what kind of "isolation" did those people go through, that died? I freely admit that I've joked about how all of the preppers who had their bunkers or survival closets stocked full of Jim Bakker 'Bucket of Mashed Potatoes that will feed a family of five for a year' were melting down that they couldn't go to SuperCuts or eat in at Chili's, but what did isolation look like for the people you are talking about? Because I always felt like we were never fully isolated - we could still get out and walk or drive around, or put on our masks and go stand 6 feet apart in HEB.
  17. They've got three young kids (she had I think all three within 3-4 years). Miller is in D.C. as long as Trump is. If she packs up the kids and follows Musk back to Austin...Miller getting cucked by Musk so publicly...
  18. So Austin Energy says power outages are down from 62,000 people to 52,000 people.
  19. Are we talking about a constantly self-improving boulangerie owner from Belgium with low grade narcolepsy?
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