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Posted
3 minutes ago, Vanilla Strange Gato said:

Damn.  Hope the recovery from that is quick!

 

Also hope you were heavily sedated for that procedure. 

I had weak ass nitrous oxide and nothing else.  Drove home from north Austin feeling like I had to piss and shit at the same time, just like normal traffic.

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Posted
11 minutes ago, Vanilla Strange Gato said:

Nope. I am gonna need to be out for that 

Hope you never need to deal with it.  Not pleasant but hopefully the results say I can do nothing for another couple of years.  My Gleason score and Decipher tests say low risk.  

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Posted
Had my second prostate biopsy today.  Good times.  Nothing like having a Louisville slugger with a hole punch on it stuck up your ass.  10 to 14 days until I get the results.  Hopefully the tumor is still dormant.  

But to be clear, you moaning with pleasure throughout the procedure DID give the doc some mixed signals.
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Posted
4 hours ago, Judge Roybeanbag said:

As a side note I give any gay guys credit.  Having this stuck up your butt is a teeth clinching exercise.  image.jpeg.3e2d79136590b6f3fff6f68427551fdd.jpeg

Good thing they put a rubber on that plastic prong, else youda been drippin with robot jizz on your Walk of Shame you lil hoochie.

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Posted
4 hours ago, Sbbruin said:

Well FUCK CANCER #154,785.  My brother called me to let me know he's been diagnosed with anal cancer.  Spread to a couple of lymph nodes, but no organs.  Starting chemo and radiation Dec 1.  Chemo combo is Mitomycin and Xeloda if anyone has had that combo.  He's flying down this weekend to just get away from it for a couple of days.  Gonna take him out on the water Saturday.  A little ocean breeze can go a long way in setting one's mind right.  But fuck, man.

Well dammit. put him in some tight swim suit because we don't need the fish all getting anal cancer too.

Seriously, nuke it from orbit.

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Posted
12 minutes ago, RDCanecutter said:

Well dammit. put him in some tight swim suit because we don't need the fish all getting anal cancer too.

Seriously, nuke it from orbit.

An ass-plosion of chemo, if you will.

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Posted
On 11/6/2025 at 12:25 AM, Bevo said:

 

Do you happen to know which kinase (or other protein) the mutated gene codes for? 

It's an nrg1 protein fusion. 

 

Well, after increasing problems the last few weeks, I got the call yesterday that the extensive liver tumors have started to majorly block liver function and failure is on the way. Unless some miracle happens and they start to shrink my timeline is a few weeks to a few months. 

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Posted
4 hours ago, seven said:

It's an nrg1 protein fusion. 

 

Well, after increasing problems the last few weeks, I got the call yesterday that the extensive liver tumors have started to majorly block liver function and failure is on the way. Unless some miracle happens and they start to shrink my timeline is a few weeks to a few months. 

 

That sucks. I'm very sorry to hear that news. Stay strong.

I assume they already tried zenocutuzumab (Bizengri). I can't remember offhand what else is in development, but I'll check it out. 

Posted

Seribantumab doesn't look great in clinical trials

Patritumab deruxtecan is further along but I have my doubts 

Hummingbird Biosciences has some interesting stuff but it is too early stage and for the most part being done outside the US anyway. I think the company is in Singapore. 

 

Posted (edited)
6 hours ago, Bevo said:

 

That sucks. I'm very sorry to hear that news. Stay strong.

I assume they already tried zenocutuzumab (Bizengri). I can't remember offhand what else is in development, but I'll check it out. 

Couldn't get accepted to the trial, then I think it was released recently but Medicare wouldn't approve "off-label" since it's primary is lung cancer. I took the oral version and it did nothing. I might be getting mixed up with something else though. 

Edited by seven
Posted (edited)
41 minutes ago, seven said:

Couldn't get accepted to the trial, then I think it was released recently but Medicare wouldn't approve "off-label" since it's primary is lung cancer. I took the oral version and it did nothing. I might be getting mixed up with something else though. 


 

No, that makes sense. No oral version though.

Edited by Bevo
Posted
12 hours ago, seven said:

It's an nrg1 protein fusion. 

 

Well, after increasing problems the last few weeks, I got the call yesterday that the extensive liver tumors have started to majorly block liver function and failure is on the way. Unless some miracle happens and they start to shrink my timeline is a few weeks to a few months. 

So sorry seven.  Just keep fighting the fight.  Until you just want comfort.  Then focus on that.  Buncha assholes keeping you tight in our thoughts.

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Posted
13 hours ago, Stringer said:

We did my one year bone marrow tests on Halloween and finally got the final results yesterday.  I am officially in remission at the 1 year mark.  These tests last year showed returning disease and sent us to transplant #2.  Basically, I have not been cancer free for this long in over 3 years.  By no means am I going to start spiking footballs, but it is a huge relief to get over this milestone.  Next tests are 6 months away.

For now, I am just getting my head around everything.  We have had optimism in the past and keep getting kicked down, so we are keeping celebration at a minimum.  I need to stay diligent about working out and eating healthier with minimal booze.  It sucks, but need to keep the peddle down.

As my wife and I have always said, we are just buying time.  The longer we go, the longer they will have to find better treatments.  I said last Christmas that I just wanted to see my youngest get to kindergarten.  Now, we're looking at 1st grade.  A bit at a time.

Enjoy the free baseball! Take every inning you can get.

Posted
13 hours ago, seven said:

It's an nrg1 protein fusion. 

 

Well, after increasing problems the last few weeks, I got the call yesterday that the extensive liver tumors have started to majorly block liver function and failure is on the way. Unless some miracle happens and they start to shrink my timeline is a few weeks to a few months. 

That's that cold reality pushing in.

Maybe they shrink anyway. Maybe you wake up and you're fishing with your Granddad.

I wish you well.

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